Over the past 20 years, the ICS/MCI has made important contributions to the study of gene function and to innovations that have transformed the research landscape in this field.

The objective of this conference is to open the discussion on the concepts discovered thanks to the studies conducted with the mouse and rat model organisms. By bringing together these internationally renowned scientists, working in academia and in the private sector, we will be able to share a set of discoveries that are crucial for basic research, biomedical research and therapeutic innovation.

One of the major challenges in basic and applied research is to understand the function of genes in a mammalian model organism, an essential step complementary to the genome sequencing now being carried out in several organisms. So far, genome decoding is far from achieving its ultimate goal, which is to assign functions to a given gene. Indeed, more than two thirds of genes do not have a functional annotation to date, and little information is available on non-coding regions. Therefore, understanding the disease inducing character of a gene variation in the human population is still a challenge.

Four major axes will be discussed during this event with the support of academic and industrial research actors:

- Knowledge acquired in the mouse model with impacts on fundamental or applied research for all functions and in particular in an integrated process: development, physiological and behavioural functions, ageing, responses to infections...

- The identification and understanding of variations in the genome at the origin of pathologies, whether monogenic or multifactorial, rare or more frequent.
- The discovery of new opportunities for innovation and the development of therapies and molecules that best meet society's needs.
- Improving our knowledge of the murine genome by analysing all gene functions in an integrated process (development, physiological and behavioural functions, ageing, responses to infections, etc.)

The elucidation of the function of genes in a mammalian genome will lead, among other things, to an evolution in biological research, innovative biotechnological techniques, and a better understanding of human diseases. Furthermore, this functional annotation of genes will permit the identification and validation of new targets for the development of therapeutic molecules.

Meeting venue: iCS / IGBMC-Strasbourg-France

1, rue Laurent Fries, 67400 Illkirch-Strasbourg-France

Registrations are Open!
Free but mandatory

In-person Registration Closed

Visio conference registration Closed

Contact us: ics@igbmc.fr 

Register by viosio conference only  Here: https://ics-mci.sciencesconf.org/registration